TCL Fertility-Aid™ rapidly measures oxidative stress across all biological samples. Applying thermochemiluminescence technology, the TCL Fertility-Aid™ provides a rapid and accurate view of both oxidative stress status and susceptibility to oxidation.
Measuring the status of oxidative stress in the embryo medium using the TCL Fertility-Aid™ provides a reliable indicator for embryo viability and its ability to result in a successful conception.
During assisted reproduction procedures, a small number of embryos are selected from a larger pool to be used for implantation. At this critical stage, the TCL Fertility-Aid™ can be used to help IVF practitioners optimize the selection process by providing a reliable measure for embryo viability prior to transfer.
Validity of TCL Fertility-Aid™ as an IVF success prediction has been demonstrated in pre-clinical studies.
Moreover, improving embryo selection is an important milestone towards the goal of reducing the multiple-birth rate, with the accompanying medical risk to mother and babies.
TCL Fertility-Aid™ has demonstrated two additional results related to human fertility problems. Measurements of oxidative stress in follicular fluid enable prediction of failure of the IVF procedure with a negative predictive value (NPV) of 97%.
Oxidative stress indices in seminal plasma, as measured by the thermochemiluminescence assay, correlate with sperm parameters, enabling identification of male fertility problems.
TCL Fertility-Aid™ is a compact low-cost diagnostic device that enables point-of-care analysis by healthcare professionals with no special training. TCL Fertility-Aid™ is suited for use in hospital fertility units, IVF clinics, and central laboratories.